BIOSENSOR

Measure
01

Continuous measurement, not a snapshot.

A dedicated sensor layer turns metabolic state into a live process signal, connected directly to the control stack at the vessel wall.

01
In-line
Measurement at the vessel wall, not in a separate lab
02
Continuous
Direct signal flow inside the measurement loop
03
Std.
Standard sensor ports for major vendor platforms
04
1 : 1
Dedicated electrochemical channel per analyte
05
Live
Metabolic state available as a process signal
Process signal

Metabolic state becomes a live process signal.

Target analyte
Linear range (mM)
Sensitivity (nA/mM)
LOD
Tested to
Linearity (R²)
Glucose
1 – 60
3.61 ± 0.18
0.2 mM
60 mM
0.944
Glutamate
0.1 – 20
78 ± 1.34
0.05 mM
20 mM
0.9953
Lactic acid
0.1 – 60
21 ± 0.72
0.03 mM
60 mM
0.9913
Glutamine
0.1 – 10
19.1 ± 0.45
0.01 mM
10 mM
0.9984
Lysine
0.1 – 3
128 ± 2.87
84.7 nM
3 mM
0.98
Alanine
0.1 – 15
3.53 ± 0.16
0.15 mM
15 mM
0.98
Glucose signalGlutamine signalGlutamate signalLactic acid signal
The unit

Mods of Communication.

The sensor sits in the process and reads it continuously. Getting that reading out is deliberately not tied to one route: USB-C, Bluetooth and Wi-Fi are all on the unit.

n!Biomachines Biosensor unit with process connectivity
The signal loop

Measure.Transduce.Stream.Control.

Sensor architecture

One signal path from chemistry to control.

n!Biomachines Sensors move metabolic readout into the reactor, where the culture is changing, and turn that state into a continuous in-line signal for the control stack.

01 / Position

Inside the vessel wall.

Electrochemical sensing elements sit in the process and read the metabolic state of the culture as it happens.

Sensor CAD →
02 / Channels

One channel per analyte.

Each channel is dedicated to a single analyte, creating a clear signal path from culture chemistry to process data.

Capabilities →
03 / Stream

Continuous by design.

The signal stays connected to the process, ready for inference, comparison, and control as the culture changes.

Deployment →
Capabilities

Built for the biology, not around it.

The sensor layer is designed for in-line biochemical readout: dedicated channels, standard process access, and validation across culture systems.

  • Cross-modality validation
  • Multi-parameter detection
Phase-contrast micrograph of adherent CHO cells at 100 micrometre scaleBioreactor with a live readout of pH, dissolved oxygen, CO2, temperature, glucose, lactate, glutamate and glutamine alongside a process heatmap
Deployment

Deploys on what you already have.

n!Biomachines Sensors integrate natively with AUXO V systems and retrofit onto existing third-party bioreactor infrastructure through standard sensor ports. No hardware replacement. No disruption to qualified process equipment.

AUXO V systemIntegrated

AUXO V systems

Direct integration with the n!Biomachines stack and the reactor-side control architecture.

Third-party bioreactor retrofitRetrofit

Third-party infrastructure

Installation through standard sensor ports on existing major vendor platforms without replacing qualified equipment.

Deployment

One sensor. Any format. Your metabolites.

01

Any size

From 30 µm to standard probe.

02

Any vessel

Geometry and fitting built to fit.

03

Variable channel count

Configured, not fixed.

04

Many analytes

Your panel, not ours.

Specification

Built into the process layer.

Measurement positionIn-line at the vessel wall
Signal modelContinuous electrochemical detection
Channel architectureDedicated channel per analyte
Process fitStandard sensor ports
Retrofit pathThird-party bioreactor infrastructure
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